Bosuvi contains Bosutinib, a tyrosine kinase inhibitor (TKI) prescribed for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It works by blocking abnormal proteins that promote the growth and spread of leukemia cells, helping slow disease progression.
Bosuvi (Bosutinib)
Bosuvi is an oral anticancer medication containing Bosutinib, a targeted tyrosine kinase inhibitor used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It is prescribed for eligible patients with newly diagnosed chronic-phase CML as well as for certain patients whose disease has not responded adequately to previous therapies or who cannot tolerate other tyrosine kinase inhibitors.
Bosutinib works by inhibiting abnormal BCR-ABL and Src tyrosine kinases that drive the uncontrolled growth of leukemia cells. By blocking these signaling pathways, Bosuvi helps slow the multiplication of cancer cells and supports better disease control.
Treatment with Bosuvi should always be supervised by an oncologist or a healthcare professional experienced in managing leukemia. Regular blood tests and monitoring are important throughout therapy to evaluate effectiveness and detect potential side effects.
- Targeted therapy for Philadelphia chromosome-positive CML
- Helps slow the growth of leukemia cells
- Oral once-daily tablet
- Tyrosine kinase inhibitor (TKI)
- Suitable for selected newly diagnosed and previously treated patients
- Supports long-term disease management under medical supervision
Bosutinib blocks the activity of abnormal BCR-ABL and Src tyrosine kinases responsible for the uncontrolled growth of leukemia cells. By inhibiting these enzymes, it slows the multiplication and spread of cancer cells while helping restore more normal blood cell production.
- Take exactly as prescribed by your oncologist.
- Swallow the tablet whole with water.
- Take once daily with food.
- Take the medicine at the same time each day.
- Do not crush, split, or chew the tablet unless instructed.
- If you miss a dose, follow your healthcare provider's advice rather than taking an extra dose.
Common side effects may include:
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Fatigue
- Fever
- Rash
- Low blood cell counts
- Elevated liver enzymes
Seek immediate medical attention if you develop severe bleeding, persistent fever, difficulty breathing, severe diarrhea, or signs of liver injury.
- Prescription medicine only.
- Regular blood tests may be required during treatment.
- Inform your doctor if you have liver disease, heart disease, or kidney problems.
- Tell your healthcare provider about all medications you are taking, as Bosutinib has significant drug interactions.
- Avoid pregnancy during treatment and follow your doctor's recommendations regarding contraception.
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